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Updated: Feb 10, 2026

Robotic Enucleation of an Intra-Pancreatic Insulinoma in the Pancreatic Head
Published on: January 3, 2020
[Insulinoma found in patient with apparent mental disorder: a case report]
José León Chirinos-Revilla1, Jenny Gabriela Fernandez-Sivincha1
1Facultad de Medicina, Universidad Nacional de San Agustín. Arequipa, Perú; Sociedad Científica de Estudiantes de Medicina Agustinos (SOCIEMA). Arequipa, Perú.
Abstract:
Pancreatic Insulinoma is a neuroendocrine tumor of the beta cells of the islets of Langerhans, has an incidence of 4 cases per 1 000 000 persons. We report the case of a 36-year-old woman with altered behavior associated with melancholy. Psychiatry describes an abnormal mental examination and diagnosed double depression; however, the patient had the Whipple triad and insulin/glucose ratio higher than 0.3. The insulinoma was localized by magnetic resonance imaging and treated with surgery. Insulinomas can mimic mental disorders, making early diagnosis difficult. We compare health care data in our locality with others obtained from the global literature. We conclude that despite the technical limitations, insulinoma should be included in the differential diagnosis of mental disorders with hypoglycemia.
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