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Peritoneal Dialysis for AKI in Cameroon: Commercial vs Locally-Made Solutions
Dennis Palmer1, William J Lawton2,3, Charles Barrier4,5
1Mbingo Baptist Hospital, Mbingo, Cameroon.
Summary
Locally produced peritoneal dialysis (PD) solutions offer a cost-effective alternative for acute kidney injury (AKI) treatment in resource-limited settings. Mortality and peritonitis rates were similar compared to commercial PD solutions.
Area of Science:
- Nephrology
- Public Health
- Medical Technology
Background:
- Acute kidney injury (AKI) presents a significant mortality challenge in low- and middle-income countries, often due to limited dialysis capabilities.
- Peritoneal dialysis (PD) is a cost-effective option for AKI in resource-limited settings, but commercial solutions remain expensive.
Purpose of the Study:
- To evaluate the outcomes and peritonitis rates of acute kidney injury (AKI) patients treated with peritoneal dialysis (PD) using either commercial or locally-produced PD solutions.
- To assess the feasibility and safety of using locally-made PD solutions in resource-limited environments.
Main Methods:
- A retrospective cohort study was conducted comparing patients with AKI treated with commercial PD solutions versus locally-produced PD solutions.
- Data on mortality and peritonitis rates were collected from patients treated at Mbingo Baptist Hospital in Cameroon between May 2013 and March 2017.
Main Results:
- Mortality rates for AKI patients were 28% with commercial solutions and 33% with locally-produced solutions.
- Peritonitis occurred in 16% of PD treatment courses in both the commercial and locally-produced solution groups.
Conclusions:
- Locally produced PD solutions, when used with available tubing, demonstrated comparable mortality and peritonitis rates to commercial supplies for AKI treatment.
- This suggests that locally-produced PD solutions are a viable and safe option for managing AKI in resource-limited settings.
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