Related Experiment Video
Updated: Feb 10, 2026
10:46
Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
19.3K
Optical Coherence Tomography Angiography in Glaucoma: A Review.
Ophthalmic Research
|May 26, 2018
Summary
Optical coherence tomography angiography (OCTA) shows high repeatability and can differentiate normal from glaucoma eyes. This noninvasive technique is valuable for glaucoma diagnosis, follow-up, and detecting disease progression.
Area of Science:
- Ophthalmology
- Medical Imaging
- Glaucoma Research
Background:
- Glaucoma is a leading cause of irreversible blindness globally.
- Current diagnostic and follow-up methods for glaucoma are varied.
- Optical coherence tomography angiography (OCTA) offers noninvasive, quantitative assessment of retinal and choroidal microcirculation.
Purpose of the Study:
- To review the literature on the application of OCTA in glaucoma diagnosis and management.
- To synthesize current findings on OCTA's role in ophthalmology.
Main Methods:
- Comprehensive literature search conducted across MEDLINE, Embase, and Web of Science databases.
- Inclusion of original research articles published up to July 23, 2017.
- Systematic review of OCTA's diagnostic and prognostic capabilities in glaucoma.
Main Results:
- OCTA demonstrates high repeatability and reproducibility.
- OCTA effectively differentiates healthy eyes from those with glaucoma.
- OCTA correlates better with visual function than conventional OCT and detects progression.
- OCTA shows potential for early glaucoma detection, comparable to OCT.
Conclusions:
- OCTA exhibits significant potential for integration into routine glaucoma care.
- The technique's ability to assess microcirculation aids in glaucoma diagnosis and monitoring.
- Further research may solidify OCTA's role in managing glaucoma patients.
Related Concept Videos
01:10Review and Preview
8.4K
In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
Percentiles are a type of fractile that partition data into...
8.4K
01:13Review and Preview
11.6K
Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
11.6K
01:25Glaucoma: Overview
1.4K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.4K
01:27Open Angle Glaucoma: Treatment
1.0K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.0K
01:28Angle Closure Glaucoma: Treatment
1.3K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.3K
01:10Computed Tomography
8.8K
Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
8.8K