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Published on: August 25, 2020
Eosinophilia as a treatable trait in three patients with asthma and COPD
James Michael Ramsahai1,2, Jodie Simpson1, Peter Wark1
1Hunter Medical Research Institute University of Newcastle New Lambton NSW Australia.
Abstract:
The combination of asthma and chronic obstructive pulmonary disease (COPD) in an individual can present significant challenges to achieving satisfactory outcomes. More recently, the concepts of precision medicine and treatable traits have arisen as promising tools to improve care for this group. In this series, we present three cases of patients with features of both asthma and COPD in addition to peripheral blood eosinophilia. The novel implementation of personalized management of the individual based on this treatable trait (eosinophilia) resulted in significant benefits. These benefits included improvement in symptoms, lung function, and a marked decline in critical care admissions and exacerbation rates.
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