WITHDRAWN: Resorbable versus titanium plates for facial fractures
Mojtaba Dorri1, Richard Oliver
1Department of Restorative Dentistry, Bristol Oral and Dental School, Lower Maudlin Street, Bristol, UK, BS1 2LY.
The Cochrane Database of Systematic Reviews
|May 26, 2018
Summary
No clinical trials exist comparing bioresorbable fixation systems with titanium systems for facial fractures. Current evidence suggests bioresorbable plates may not be as effective as titanium plates.
Area of Science:
- Orthopedic surgery
- Biomaterials science
- Medical device development
Background:
- Rigid internal fixation using titanium plates and screws is standard for managing facial fractures.
- Bioresorbable fixation systems offer potential advantages, including eliminating the need for a second surgery.
- Concerns exist regarding bioresorbable systems' stability, degradation time, and potential for foreign body reactions.
Purpose of the Study:
- To compare the effectiveness of bioresorbable fixation systems versus titanium systems in managing facial fractures.
- To systematically review existing randomized controlled trials (RCTs) on this topic.
Main Methods:
- A comprehensive literature search was conducted across multiple databases (Cochrane, MEDLINE, EMBASE, clinicaltrials.gov) up to August 20, 2008.
- Inclusion criteria focused on RCTs comparing resorbable and titanium fixation systems for facial fractures.
- Data analysis was planned using random-effects models for continuous and dichotomous outcomes.
Main Results:
- The search identified 53 potentially eligible studies, but none met the inclusion criteria.
- One study is awaiting classification; three ongoing trials were retrieved, two of which were stopped early.
- One trial was halted due to excess complications in the bioresorbable fixation group.
Conclusions:
- There is a lack of published RCTs comparing bioresorbable and titanium fixation systems for facial fractures.
- Insufficient evidence currently exists to determine the effectiveness of bioresorbable systems compared to titanium.
- Preliminary findings from aborted trials suggest bioresorbable plates may be less effective than titanium plates, necessitating well-designed future trials.
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