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Updated: Feb 10, 2026

Myocardial Infarction and Functional Outcome Assessment in Pigs
Published on: April 25, 2014
[Diagnosis of myocardial infarction in patients with cardiac pacing]
1Service de médecine interne générale, HUG, 1211 Genève 14.
Insights
Diagnosing acute coronary syndrome is challenging in patients with cardiac pacing due to altered electrocardiogram (ECG) criteria. This review covers ECG changes and cardiac memory to prevent misdiagnosis of myocardial ischemia.
Area of Science:
- Cardiology
- Electrocardiography
- Cardiac Electrophysiology
Context:
- Acute coronary syndrome (ACS) diagnosis is complicated in patients with cardiac pacing.
- Standard ECG criteria for ischemia are unreliable with ventricular paced rhythms.
- Previous myocardial infarction further complicates ECG interpretation.
Purpose:
- To review ECG modifications in patients with cardiac pacing and prior myocardial infarction.
- To discuss the phenomenon of cardiac memory and its impact on ischemia diagnosis.
- To provide guidance for accurate ACS diagnosis in paced rhythms.
Summary:
- This article examines ECG changes in patients with cardiac pacing, particularly ventricular pacing.
- It addresses the diagnostic challenges posed by previous myocardial infarction.
- The role of cardiac memory in potentially causing false-positive ischemia diagnoses is explored.
Impact:
- Improved diagnostic accuracy for acute coronary syndrome in patients with cardiac pacing.
- Reduced misdiagnosis of myocardial ischemia due to paced rhythms and cardiac memory.
- Enhanced clinical decision-making for cardiologists managing these complex cases.
Abstract:
Diagnosis of an acute coronary syndrome in patients with cardiac pacing can be difficult, as the usual ECG criteria for ischemia may not apply in case of a ventricular paced rhythm. This article discusses the ECG modifications observed in this setting, as well as in case of previous myocardial infarction. In addition, we discuss the phenomenon of cardiac memory, which may lead to erroneous diagnosis of myocardial ischemia.
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