[The features of c/oVEMP in patient with unilateral Meniere's disease]

Objective:To evaluate the difference in c/oVEMPs between patients with MD and normal controls.Method:Twenty-two patients with unilateral MD and 21 healthy subjects (as normal controls) were prospectively examined with c/oVEMPs. The results were compared between these two groups. MD group were divided into two groups according to the pure tone average threshold: group1 PTA≤40 dBnHL,group2 PTA>40 dBnHL,and then compared their results. A commercially available software package SPSS 19.0 was used for statistical analysis.Result:The latency and amplitude of cVEMP and oVEMP in the affected side and contralateral side of the MD group were no significant difference. Compared with normal controls,the latency of P1 and N1 was prolonged,the amplitude was decreased in the MD group's cVEMP. The amplitude was decreased in the MD group's oVEMP,but the latency was not prolonged. Group 2's extraction rate of cVEMP was significantly lower than group 1.Conclusion:An increased occurrence of abnormal c/oVEMP recordings appeared in MD patients,possibly as a result of hydrops of the otolith. The saccular dysfunction may be more common than utricular dysfunction. Furthermore,that otolith damage is gradually increasing with the aggravation of cochlear injury in MD.