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[Management of chronic rhinosinusitis]
Summary
Chronic rhinosinusitis (CRS) is a common upper airway inflammation affecting nasal and sinus tissues. Effective management requires individualized, long-term anti-inflammatory treatment, with surgery considered for persistent or recurrent symptoms.
Area of Science:
- Otolaryngology
- Allergy and Immunology
- Respiratory Medicine
Background:
- Chronic rhinosinusitis (CRS) is a prevalent upper respiratory disorder characterized by persistent inflammation of the nasal and paranasal sinus mucosa.
- CRS is clinically classified into two main phenotypes: chronic rhinosinusitis with nasal polyps (CRSwNP) and chronic rhinosinusitis without nasal polyps (CRSsNP).
Purpose of the Study:
- To outline the current understanding of chronic rhinosinusitis (CRS) management strategies.
- To emphasize the importance of long-term anti-inflammatory treatment as the cornerstone of CRS therapy.
- To define the role of surgical intervention in refractory CRS cases.
Main Methods:
- Review of current medical and surgical treatment paradigms for CRS.
- Discussion of the indications for surgical intervention in CRS management.
- Consideration of CRS phenotypes and endotypes in treatment planning.
Main Results:
- Long-term anti-inflammatory therapy is crucial for managing CRS.
- Surgery is indicated for symptomatic CRS cases unresponsive to maximal medical treatment.
- Surgical intervention may serve as an adjunct therapy for recurrent CRS.
Conclusions:
- Effective CRS management necessitates a long-term anti-inflammatory approach.
- Surgical treatment is reserved for persistent or recurrent cases after medical optimization.
- Future CRS management will increasingly rely on individualized treatment strategies based on distinct patient phenotypes and endotypes.
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