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Updated: Feb 10, 2026
09:21
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
12.7K
[Ischemic stroke in the patients with comorbid pathology].
V I Larkin1, A A Bort2, T A Lisina1
1Omsk State Medical University, Omsk, Russia.
Summary
Comorbidity significantly impacts ischemic stroke outcomes, with increased severity predicting poorer results and survival. This finding is crucial for managing acute ischemic stroke patients in specialized settings.
Area of Science:
- Neurology
- Cardiology
- Geriatrics
Background:
- Ischemic stroke (IS) is a leading cause of disability.
- The influence of comorbidity on IS course and outcome requires further elucidation.
Purpose of the Study:
- To investigate the effect of comorbidity on the course and outcome of ischemic stroke (IS).
Main Methods:
- Retrospective cohort study of 190 IS patients.
- Assessment of stroke severity (NIHSS), daily dependence (Rankin scale), and comorbidity (CCI, CIRS).
Main Results:
- A correlation was found between IS severity/outcome and comorbidity severity (CCI, CIRS).
- Comorbidity severity increased with patient age.
- Comorbidity (CCI) and stroke severity (NIHSS) predicted IS outcome (Rankin scale) (R=0.722, R²=0.521, p=0.0026).
- Comorbidity was shown to affect stroke survivability.
Conclusions:
- Comorbidity is a significant predictor of ischemic stroke outcome and survival.
- Findings support the integration of comorbidity assessment in acute IS management.
- Age is associated with increased comorbidity burden in IS patients.
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