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Updated: Feb 10, 2026

A Technique to Functionalize and Self-assemble Macroscopic Nanoparticle-ligand Monolayer Films onto Template-free Substrates
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Brain Targeting Delivery Facilitated by Ligand-Functionalized Layered Double Hydroxide Nanoparticles

Weiyu Chen, Huali Zuo, Enqi Zhang1

  • 1Otto-von-Guericke University , Magdeburg 39106 , Germany.

ACS Applied Materials & Interfaces
|May 26, 2018
PubMed
Summary

Researchers developed a novel nanoplatform using layered double hydroxide (LDH) nanoparticles. Angiopep-2 (Ang2) modification enhances brain targeting and delivery for treating brain diseases.

Keywords:
blood-retina targetingblood−brain barrierbovine serum albumin coatingbrain target peptidelayered double hydroxide

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