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Updated: Aug 13, 2026

Percutaneous Contrast Echocardiography-guided Intramyocardial Injection and Cell Delivery in a Large Preclinical Model
Published on: January 21, 2018
Cardiac neoplasms: current diagnosis, pathology, and therapy
1Department of Surgery, University of Kentucky Medical Center, Lexington 40536-0084.
Cardiac neoplasms, both benign and malignant, present diagnostic and therapeutic challenges. Advances in imaging and surgical techniques offer improved management for benign tumors, while malignant tumors remain a significant challenge.
Area of Science:
- Cardiology
- Oncology
- Surgical Oncology
Background:
- Cardiac neoplasms are rare with diverse clinical presentations.
- Diagnosis and surgical removal of benign cardiac tumors can be complex.
- Malignant cardiac tumors, primary or metastatic, pose significant therapeutic hurdles.
Purpose of the Study:
- To review diagnostic, pathological, and therapeutic aspects of cardiac neoplasms.
- To detail surgical approaches for resectable cardiac tumors.
- To highlight advancements in managing benign cardiac tumors.
Main Methods:
- Comprehensive literature review of cardiac neoplasms.
- Analysis of diagnostic modalities, including intraoperative transesophageal echocardiography.
- Examination of pathological and histological findings.
- Review of surgical techniques and therapeutic strategies.
Main Results:
- Intraoperative transesophageal echocardiography aids surgical planning for benign tumors.
- Cardiac transplantation offers an option for unresectable benign neoplasms.
- Electrophysiologically guided surgery can control arrhythmias from benign tumors.
- Limited progress has been made in treating malignant cardiac tumors.
Conclusions:
- Benign cardiac neoplasms require careful diagnosis and tailored surgical approaches.
- Advanced imaging and techniques improve outcomes for benign cardiac tumors.
- Malignant cardiac tumors necessitate further research and novel therapeutic strategies.
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