Subclinical atrial fibrillation frequency and associated parameters in patients with cardiac resynchronization

Mehmet Uğurlu1, Onur Kaypakli2, Durmuş Yıldıray Şahin1

  • 1Department of Cardiology, University of Health Sciences - Adana Health Practices and Research Center, Adana, Turkey.

Insights

Subclinical atrial fibrillation (SCAF) is common in cardiac resynchronization therapy (CRT) patients. Left atrial diameter, CHA2DS2-VASc score, and atrial threshold independently predict SCAF risk.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Subclinical atrial fibrillation (SCAF) poses risks like stroke in cardiac resynchronization therapy (CRT) patients.
  • Identifying SCAF is crucial for managing anticoagulation therapy in CRT recipients.

Purpose of the Study:

  • To determine the frequency of SCAF in patients undergoing CRT.
  • To identify clinical and device-related parameters associated with SCAF development.

Main Methods:

  • 191 CRT patients (mean age 65.9 years) were monitored for atrial high-rate episodes.
  • SCAF was defined as asymptomatic episodes lasting 6 minutes to 24 hours.
  • Device parameters including atrial lead thresholds and P-wave amplitude were analyzed.

Main Results:

  • SCAF was detected in 23.2% of CRT patients.
  • Left atrial diameter, CHA2DS2-VASc score, and atrial threshold were independent predictors of SCAF.
  • Increased LA diameter and CHA2DS2-VASc score significantly elevated SCAF risk.

Conclusions:

  • CRT patients exhibit a higher prevalence of SCAF compared to the general population.
  • CHA2DS2-VASc score, LA diameter, and atrial threshold are valuable, accessible markers for identifying SCAF risk.
Abstract

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