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Medication adherence patterns in aortic dissection survivors.

Ashish Chaddha1, Steven Erickson1, Eva Kline-Rogers1

  • 1Frankel Cardiovascular Center, University of Michigan, Ann Arbor, Michigan, USA.

The Indian Journal of Medical Research
|May 29, 2018
PubMed
Summary
This summary is machine-generated.

Medication adherence in acute aortic dissection (AAD) survivors was 64%, with non-adherence linked to chest pain recurrence. Clinicians should emphasize antihypertensive therapy importance and assess patient forgetfulness.

Keywords:
Angiotensin-converting enzyme inhibitorsantihypertensiveaortaaortic diseaseaortic dissectionbeta-blockersblood pressurecalcium-channel blockers

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Area of Science:

  • Cardiovascular Medicine
  • Medical Outcomes Research

Background:

  • Beta-blockers improve survival in acute aortic dissection (AAD) types A and B.
  • Calcium channel blockers selectively benefit type B AAD patients.
  • Limited data exists on medication adherence in AAD survivors.

Purpose of the Study:

  • To assess medication adherence among patients who survived acute aortic dissection.
  • To identify factors influencing medication adherence in AAD survivors.

Main Methods:

  • Cross-sectional, survey-based study of AAD survivors from a single medical center.
  • Utilized data from the International Registry of Acute Aortic Dissection (IRAD).
  • Assessed medication adherence using the 4-item Morisky scale.

Main Results:

  • 64% of AAD survivors demonstrated medication adherence based on the Morisky scale.
  • Non-adherence (Morisky score ≥1.0) was associated with increased chest pain recurrence at one year.
  • Forgetfulness and carelessness were reported by 33% and 8% of patients, respectively.

Conclusions:

  • A significant proportion of AAD survivors exhibit suboptimal medication adherence.
  • Clinicians should reinforce the importance of antihypertensive therapy and screen for adherence barriers.
  • Addressing patient beliefs and forgetfulness can improve medication adherence in AAD survivors.