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B Fougère1, J E Morley, M O Little
1Bertrand Fougère, Institut du Vieillissement, Gérontopôle, Université Toulouse III Paul Sabatier, 37 Allées Jules Guesde, 31000 Toulouse, France. Tel: +33561145657 ; fax: +33561145640.
The Journal of Nutrition, Health & Aging
|May 29, 2018
Summary
Effective interventions are needed to combat frailty in older adults. Multidomain approaches show promise in preventing or delaying disability, addressing the growing global healthcare challenge.
Area of Science:
- Geriatrics
- Public Health
- Aging Research
Background:
- Global population aging is increasing the prevalence of frailty.
- Frailty is a geriatric syndrome of age-associated physiological decline, increasing vulnerability and adverse health outcomes.
- Rising healthcare and long-term care expenditures necessitate effective prevention and management strategies.
Purpose of the Study:
- To review recent literature on interventions aimed at reversing or delaying disability in frail older adults.
- To identify effective strategies for managing frailty, a growing global health concern.
Main Methods:
- Literature review of studies on pharmacological, physical activity, nutritional, and cognitive interventions for frail older adults.
- Analysis of ongoing trials, particularly those focusing on multidomain interventions.
Main Results:
- Pharmacological, physical activity, nutritional, and cognitive interventions have shown efficacy in frail older adults.
- Multidomain interventions represent an important innovation in frailty management.
Conclusions:
- Reversing frailty requires a comprehensive, multidimensional approach.
- Challenges remain in trial design, outcome measure standardization, and implementation in resource-poor settings.
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