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Updated: Feb 10, 2026

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
PET/CT Interpretative Pitfalls in Thoracic Malignancies
Girish S Shroff1, Bradley S Sabloff1, Mylene T Truong1
1Department of Diagnostic Radiology, University of Texas MD Anderson Cancer Center, Houston, TX.
Abstract:
Applications of positron emission tomography/computed tomography (PET/CT) in the thorax include the evaluation of solitary pulmonary nodules, staging and restaging of oncologic patients, assessment of therapeutic response, and detection of residual or recurrent disease. Accurate interpretation of PET/CT requires knowledge of the physiological distribution of [18F]-fluoro-2-deoxy-D-glucose, as well as artifacts and quantitative errors due to the use of CT for attenuation correction of the PET scan. Potential pitfalls include malignancies that are PET negative and benign conditions that are PET positive. Awareness of these artifacts and potential pitfalls is important in preventing misinterpretation that can alter patient management.
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