Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

542
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
542
Endocarditis I: Introduction01:25

Endocarditis I: Introduction

518
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
518
Endocarditis III: Medical Management01:18

Endocarditis III: Medical Management

265
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
265
Endocarditis IV: Nursing Management01:29

Endocarditis IV: Nursing Management

398
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
398
Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

758
Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
758
Anatomy of the Heart01:27

Anatomy of the Heart

120.1K
The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
120.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effect of Non-nucleoside Resistance-Associated Mutations on the Effectiveness of Long-Acting Cabotegravir + Rilpivirine Therapy: Insights From the Real-World RELATIVITY Cohort.

Open forum infectious diseases·2026
Same author

Adherence to Hepatocellular Carcinoma Surveillance Guidelines Among People with HIV and Chronic HBV Infection.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2026
Same author

Clinical Experience of Ceftaroline Fosamil in Gram-Positive Infective Endocarditis: A Multicenter Real-World Observational Study.

Antibiotics (Basel, Switzerland)·2026
Same author

ASP-COMPLEX: redefining antimicrobial stewardship to improve outcomes in high-risk patients with severe infections.

Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia·2026
Same author

Hepatotoxicity in HIV-tuberculosis coinfection: From a known risk to a preventable complication.

Enfermedades infecciosas y microbiologia clinica (English ed.)·2026
Same author

Bictegravir/emtricitabine/tenofovir alafenamide: A review of the real-world experience in Spain within the last five years.

Enfermedades infecciosas y microbiologia clinica (English ed.)·2026

Related Experiment Video

Updated: Feb 10, 2026

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat

Published on: June 4, 2012

17.6K

Left endocarditis, changes in the new millennium.

Mariam Noureddine-López1, Javier de la Torre-Lima1, Josefa Ruiz-Morales2

  • 1Grupo de Enfermedades Infecciosas de la Unidad de Medicina Interna, Hospital Costa del Sol, Marbella, Málaga, España.

Medicina Clinica
|May 30, 2018
PubMed
Summary

Infective endocarditis patients in the new millennium are older with more comorbidities, yet mortality remains stable around 30%. This is due to increased healthcare-associated infections and more aggressive microorganisms, despite treatment advances.

Keywords:
Endocarditis infecciosaEpidemiologyEpidemiologíaInfective endocarditisMortalidadMortalityNosocomial

More Related Videos

Orthotopic Left Lung Transplantation in Rats
08:22

Orthotopic Left Lung Transplantation in Rats

Published on: July 3, 2025

757
A Method to Study Adaptation to Left-Right Reversed Audition
07:14

A Method to Study Adaptation to Left-Right Reversed Audition

Published on: October 29, 2018

6.9K

Related Experiment Videos

Last Updated: Feb 10, 2026

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat
07:46

Experimental Endocarditis Model of Methicillin Resistant Staphylococcus aureus MRSA in Rat

Published on: June 4, 2012

17.6K
Orthotopic Left Lung Transplantation in Rats
08:22

Orthotopic Left Lung Transplantation in Rats

Published on: July 3, 2025

757
A Method to Study Adaptation to Left-Right Reversed Audition
07:14

A Method to Study Adaptation to Left-Right Reversed Audition

Published on: October 29, 2018

6.9K

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Epidemiology

Background:

  • Infective endocarditis (IE) presents unique challenges at the turn of the millennium.
  • Understanding epidemiological shifts in IE is crucial for effective management.

Purpose of the Study:

  • To describe infective left endocarditis (IE) at the turn of the millennium.
  • To compare IE patient characteristics and outcomes between two distinct periods (1983-1999 and 2000-2014).

Main Methods:

  • A multicentre prospective study of the Andalusian cohort for cardiovascular infections.
  • Data collected from 1,604 IE cases between 1983 and 2014, divided into two groups: 1983-1999 (G1) and 2000-2014 (G2).

Main Results:

  • Patients in the new millennium (G2) were older, had higher comorbidity, and more frequent nosocomial IE.
  • An increase in methicillin-resistant Staphylococcus aureus, Enterococcus sp., Gram-negative bacilli, and Streptococcus bovis was observed.
  • Despite treatment changes and increased surgery, mortality remained stable at approximately 30% in both periods.

Conclusions:

  • Stable mortality rates in IE are attributed to older patients, increased comorbidity, nosocomial infections, and more aggressive pathogens.
  • Multivariate analysis identified age, comorbidity, renal failure, septic shock, and Staphylococcus aureus as key factors associated with mortality.