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[Comparative evaluation of the accumulation of 99mTc-labeled phosphate compounds in the bones]
Abstract:
Distribution of osteotropic radiopharmaceuticals was studied in bone, different organs and tissues of rats. 99mTc-pyrophosphate (USSR and France) and 99mTc-diphosphonate (GDR and Hungary) were investigated. Differences in their behaviour were demonstrated. According to a degree of accumulation in the bone tissue, the preparations may be arranged as follows: 99mTc-diphosphonate (GDR), 99mTc-diphosphonate (Hungary), 99mTc-pyrophosphate (USSR and France).