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Updated: Feb 9, 2026

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
Published on: November 23, 2012
Galactocele, Pitfall for the Evaluation by 18F-FDG PET/CT
Quentin Ceyrat1, Caroline Ziade2, Ghoufrane Tlili3
1From the Nuclear Medicine Department, Pellegrin Hospital.
High F-FDG uptake in breast lesions on PET/CT scans can indicate galactocele, not just cancer. This finding is crucial for accurate diagnosis in postpartum women, especially those breastfeeding.
Area of Science:
- Oncology
- Radiology
- Nuclear Medicine
Background:
- Positron Emission Tomography/Computed Tomography (PET/CT) is vital for cancer staging.
- F-Fluorodeoxyglucose (F-FDG) uptake can be elevated in various inflammatory and benign conditions.
- Postpartum physiological changes can alter imaging findings.
Observation:
- A 36-year-old woman presented with diffuse large B-cell lymphoma requiring initial staging via PET/CT.
- Mammary lesions exhibited high F-FDG uptake on the PET/CT scan.
- The patient was 2 months postpartum and breastfeeding at the time of the scan.
Findings:
- Ultrasound-guided fine-needle aspiration of a mammary lesion revealed creamy liquid consistent with milk.
- The diagnosis of galactocele was confirmed.
- The high F-FDG uptake in the mammary lesion was attributed to galactocele, a benign condition.
Implications:
- High F-FDG uptake in mammary lesions during cancer staging warrants careful consideration of benign postpartum conditions like galactocele.
- Distinguishing galactocele from malignancy is critical to avoid unnecessary interventions.
- This case highlights the importance of clinical context and patient history in interpreting PET/CT findings in breastfeeding women.
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