Related Experiment Video
Updated: Feb 9, 2026

05:56
Exploring Caspase Mutations and Post-Translational Modification by Molecular Modeling Approaches
Published on: October 13, 2022
1.8K
The Role and Value of Symptom-Modification Approaches in Musculoskeletal Practice
Summary
This viewpoint explores symptom modification, a common goal in musculoskeletal physical therapy aiming to reduce pain and improve function. It examines its role in rehabilitation across different clinical models.
Area of Science:
- Musculoskeletal physical therapy
- Rehabilitation science
- Pain management
Background:
- Diverse models of care in musculoskeletal physical therapy can be confusing.
- A common underlying theme is symptom modification.
- Symptom modification focuses on reducing symptoms and enhancing function.
Purpose of the Study:
- To explore the role of symptom modification in rehabilitation.
- To examine symptom modification within the kinesiopathological model of pain.
- To identify commonalities in divergent clinical practice models.
Main Methods:
- Viewpoint article.
- Exploration of clinical practice models.
- Analysis of the kinesiopathological model of pain.
Main Results:
- Symptom modification is a unifying concept in musculoskeletal rehabilitation.
- Different approaches share the goal of symptom reduction and functional improvement.
- Potential commonalities exist despite model divergence.
Conclusions:
- Symptom modification serves as a central principle in musculoskeletal physical therapy.
- Understanding this commonality can clarify care models for patients and clinicians.
- Further exploration can unify seemingly disparate approaches to rehabilitation.
Related Concept Videos
Histone Modification
16.2K
The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
Acetylation
The enzyme histone acetyltransferase adds acetyl group to the histones. Another enzyme, histone...
Acetylation
The enzyme histone acetyltransferase adds acetyl group to the histones. Another enzyme, histone...
16.2K
Histone Modification
4.5K
4.5K
Spreading of Chromatin Modifications
9.5K
The histone proteins in the nucleosomes are post-translationally modified (PTM) to increase or decrease access to DNA. The commonly observed PTMs are methylation, acetylation, phosphorylation, and ubiquitination of lysine amino acids in the histone H3 tail region. These histone modifications have specific meaning for the cell. Hence, they are called "histone code". The protein complex involved in histone modification is termed as "reader-writer" complex.
Writers
The writer...
Writers
The writer...
9.5K
Diabetes: Symptoms, Diagnosis, and Complications
2.4K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
2.4K
Negative and Cognitive Symptoms of Schizophrenia
617
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
617
Behavior Modification
726
Behavioral approaches have often been criticized for ignoring mental processes and focusing solely on observable behavior. However, these approaches provide an optimistic perspective for individuals seeking to change their behaviors. Rather than concentrating on intrinsic personality traits, behavioral approaches suggest that even longstanding habits can be modified by changing the reward contingencies that maintain them.
A real-world application of operant conditioning principles is applied...
A real-world application of operant conditioning principles is applied...
726

