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Changes induced in rabbit plasma and aqueous humour by ACTH4-10 and ACTH1-24
Endocrinologia Experimentalis
|March 1, 1985
Abstract:
In the rabbit the effect of a single i.m. dose of ACTH4-10 (130 micrograms kg-1) was compared with that of ACTH1-24 (20 micrograms kg-1). In contrast to ACTH1-24 the heptapeptide ACTH4-10 did not stimulate the adrenal secretion of corticosterone. Both ACTH fragments induced a slight hyperglycemia and in the aqueous humour they increased the concentration of proteins.