Related Experiment Video
Updated: Feb 9, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
A Cognitive Occupation-Based Programme for People with Multiple Sclerosis: A Study to Test Feasibility and Clinical
1Discipline of Occupational Therapy, National University of Ireland Galway, Galway, Ireland.
The Cognitive Occupation-Based Programme for People with Multiple Sclerosis (COB-MS) significantly improved daily functioning and cognitive abilities in individuals with MS. This holistic approach shows promise for managing cognitive impairments in multiple sclerosis.
Area of Science:
- Neurorehabilitation
- Cognitive Science
- Multiple Sclerosis Research
Background:
- Cognitive impairments are prevalent in Multiple Sclerosis (MS), impacting daily life and occupational functioning.
- Existing cognitive rehabilitation strategies lack a validated, holistic approach for MS patients.
- There is a need to evaluate comprehensive programs addressing both cognitive and daily living aspects.
Purpose of the Study:
- To assess the effectiveness of the Cognitive Occupation-Based Programme for People with Multiple Sclerosis (COB-MS).
- To determine if COB-MS improves daily life functioning and cognitive impairments in individuals with MS.
- To evaluate the program's impact on various cognitive domains and functional outcomes.
Main Methods:
- An experimental pretest/posttest design with an eight-week follow-up was employed.
- Twelve participants (aged 39-73) with MS were recruited via convenience sampling.
- Primary outcome was the Goal Attainment Scaling (GAS); secondary outcomes included OSA-DLS, CVLT-II, BVMT-R, SDMT, TMT, BRIEF-A, and EMQ-R.
Main Results:
- Statistically significant improvements were observed in GAS, CVLT-II (total, short, and long delay free recall), BVMT-R (total recall), TMT part B, and EMQ-R.
- Clinically significant improvements were noted in most secondary outcome measures at posttest and follow-up, with the exception of BRIEF-A.
- The COB-MS intervention demonstrated positive effects on cognitive performance and functional abilities.
Conclusions:
- The Cognitive Occupation-Based Programme for People with Multiple Sclerosis (COB-MS) shows effectiveness in improving daily life and cognitive measures.
- The findings suggest that a holistic, occupation-based approach is beneficial for managing cognitive deficits in MS.
- A larger-scale study is warranted to further validate these promising results for cognitive rehabilitation in MS.
Related Concept Videos
Cognitive Dissonance
Bioavailability Study Design: Single Versus Multiple Dose Studies
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Predicting Reaction Outcomes
Outcomes of Glycolysis
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
Case Studies

