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Related Concept Videos

Tissues01:18

Tissues

85.6K
Cells with similar structure and function are grouped into tissues. A group of tissues with a specialized function is called an organ. There are four main types of tissue in vertebrates: epithelial, connective, muscle, and nervous.
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Tissues01:25

Tissues

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Tissues are a group of cells that share a common embryonic origin. Microscopic observation reveals that the cells in a tissue share morphological features and are arranged in an orderly pattern to perform specific functions. From an evolutionary perspective, tissues appear in more complex organisms. Although there are many types of cells in the human body, they are organized into four broad categories of tissues: epithelial, connective, muscle, and nervous. Each of these categories is...
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Plant Cells and Tissues02:01

Plant Cells and Tissues

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Plant tissues are collections of similar cells performing related functions. Different plant tissues will have their own specialized roles and can be combined with other tissues to form organs such as flowers, fruit, stem, and leaves. Two major types of plant tissue include meristematic and permanent tissue.
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Plant Tissue Culture02:57

Plant Tissue Culture

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Plant tissue culture is widely used in both primary and applied science. Applications range from plant development studies to functional gene studies, crop improvement, commercial micropropagation, virus elimination, and conservation of rare species.
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Gas Chromatography: Sample Injection Systems01:08

Gas Chromatography: Sample Injection Systems

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In gas chromatography, the sample is introduced as a vapor plug into the carrier gas stream for high efficiency and resolution. A microsyringe injects the sample solution into a heated sample port, vaporizing it and mixing it with the carrier gas. This process is important to ensure the sample is properly prepared for analysis. Thermally sensitive samples can be injected directly into the column and volatilized by slowly increasing the column temperature.
Two primary injection methods are used...
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Tissue Membranes01:27

Tissue Membranes

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A tissue membrane is a thin layer of cells that covers the outside of the body, the organs, internal passageways that lead to the exterior of the body, and the lining of the moveable joint cavities. There are two basic types of tissue membranes— connective tissue and epithelial membranes.
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Related Experiment Video

Updated: Feb 9, 2026

Intramuscular Injections Along the Motor End Plates: A Minimally Invasive Approach to Shuttle Tracers Directly into Motor Neurons
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Necrotizing Soft Tissue Fasciitis after Intramuscular Injection.

Angelica Abbate1, Piero Luigi Almasio2, Martina Mongitore1

  • 1General Surgery Unit, Department of Surgical, Oncological and Stomatological Sciences, University of Palermo, Palermo, Italy.

Case Reports in Surgery
|June 2, 2018
PubMed
Summary

Necrotizing soft tissue infections (NSTIs) can occur after gluteal intramuscular injections, especially in vulnerable patients. Proper injection technique is crucial to prevent severe tissue trauma and infection.

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Area of Science:

  • Infectious Diseases
  • Surgical Pathology
  • Public Health

Background:

  • Necrotizing soft tissue infections (NSTIs) are severe, uncommon infections.
  • Intramuscular injections, while common medical procedures, can lead to NSTIs.
  • Risk factors for NSTIs include immunosuppression, chronic diseases, and drug addiction.

Observation:

  • A case of NSTIs following a gluteal intramuscular injection is presented.
  • A literature review identified 19 cases of NSTIs post-intramuscular injection from 1997-2017.
  • Immunosuppressed patients, those on corticosteroids, with chronic illnesses, or drug users are particularly susceptible.

Findings:

  • Intramuscular injections can cause significant tissue trauma, creating a pathway for infection.
  • Subcutaneous injections, due to lower vascularization, increase infection susceptibility.
  • Correct injection techniques, including aspiration, may prevent intra-arterial injection and subsequent inflammation.

Implications:

  • Emphasizes the importance of meticulous injection techniques to prevent severe infections like NSTIs.
  • Highlights the need for careful patient selection and monitoring, especially in high-risk individuals.
  • Suggests that tissue necrosis at the injection site is an independent risk factor for NSTIs.