Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Directing Effect of Substituents: meta-Directing Groups01:09

Directing Effect of Substituents: meta-Directing Groups

6.0K
Substituents on the benzene ring that direct an incoming electrophile to undergo substitution at the meta position are called meta directors. All meta directors either have a positive charge on the atom directly bonded to the ring or a partial positive charge. These groups function by withdrawing electrons from the ring through inductive and resonance effects. Consider the carbocation intermediates formed upon the addition of an electrophile on nitrobenzene at the...
6.0K
Directing Effect of Substituents: ortho–para-Directing Groups01:14

Directing Effect of Substituents: ortho–para-Directing Groups

8.6K
Ortho–para directors are substituent groups attached to the benzene ring and direct the addition of an electrophile to the positions ortho or para to the substituent. All electron-donating groups are considered ortho–para directors. They donate electrons to the ring and make the ring more electron-rich. The ring is therefore susceptible to the addition of electrophiles. Substituents such as amino, hydroxy, or alkoxy, containing lone pairs on the atom adjacent to the ring, donate...
8.6K
Directional Terms01:14

Directional Terms

17.0K
Directional terms are essential for describing the relative locations of different body structures. For instance, an anatomist might describe one band of tissue as "inferior to" another, or a physician might describe a tumor as "superficial to" a deeper body structure. These terms often use comparative terms in pairs to trace out the relative locations of one body part to another or descriptions of body tissues like the deeper ones from superficially present with reference to...
17.0K
Directional Relays01:25

Directional Relays

620
Directional relays, essential for managing unidirectional fault currents, enhance the safety and efficiency of power systems. On power lines equipped with directional relays, faults downstream (to the right) of the current transformer typically cause the fault current to lag the bus voltage by approximately 90 degrees, known as the forward direction. In contrast, upstream (left-side) faults may result in the fault current leading the bus voltage by nearly 90 degrees, termed the reverse...
620
Direct Motor Pathways01:11

Direct Motor Pathways

4.5K
The direct motor pathways, also known as the pyramidal tracts, are a group of neural pathways that originate in the brain and descend through the spinal cord. They control the voluntary movement of the body. There are two major direct motor pathways: the corticospinal and the corticobulbar tracts.
The corticospinal tract is responsible for the voluntary movement of the limbs and trunk. It originates in the cerebral cortex of the brain and descends through the cerebrum's internal capsule and...
4.5K
Direction of Acceleration Vectors01:10

Direction of Acceleration Vectors

22.6K
Acceleration occurs when velocity changes in magnitude (an increase or decrease in speed), direction, or both. Although acceleration is in the direction of the change in velocity, it is not always in the direction of motion. When an object slows down, its acceleration is opposite to the direction of its motion. This is commonly referred to as deceleration. However, the term deceleration can cause confusion in analysis because it is not a vector; it does not point to a specific direction with...
22.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multimodal identification of a rare head and neck cancer patient cohort in the clinical data warehouse of Greater Paris Teaching Hospital.

ESMO real world data and digital oncology·2026
Same author

Disentangling Centrality Bias and Final-State Effects in the Production of High-p_{T} Neutral Pions Using Direct Photon in d+Au Collisions at sqrt[s_{NN}]=200  GeV.

Physical review letters·2025
Same author

Varying ENT practices in adult post-intubation laryngotracheal stenosis after the COVID epidemic in France: A CHERRIES analysis.

European annals of otorhinolaryngology, head and neck diseases·2024
Same author

In-plasma analysis of plasma-surface interactions.

The Review of scientific instruments·2023
Same author

Same-day colectomy: are we throwing caution to the wind?

Techniques in coloproctology·2023
Same author

Validation of modular endoscopic medial maxillectomies for inverted papilloma of the maxillary sinus.

Rhinology·2023
Same journal

A novel retro-muscular Sugarbaker technique for parastomal hernia prevention in end colostomy: combination of laparoscopic posterior component separation and extraperitoneal bowel pull-through-a prospective, single-arm study using the IDEAL framework.

Techniques in coloproctology·2026
Same journal

Single-stapled versus non-single-stapled colorectal anastomosis in minimally invasive anterior resections: a systematic review and meta-analysis.

Techniques in coloproctology·2026
Same journal

When nothing else matters: proctectomy for complex perianal Crohn's disease-indications, timing, techniques, and outcomes.

Techniques in coloproctology·2026
Same journal

Intermuscular dissection by transanal endoscopic operation for a rectal lesion.

Techniques in coloproctology·2026
Same journal

Predicting anatomical difficulty in robot-assisted rectal resection using a novel anatomic landmark-based grading system: a prospective observational study.

Techniques in coloproctology·2026
Same journal

Effect of home biofeedback treatment in patients with fecal incontinence: a pilot study.

Techniques in coloproctology·2026
See all related articles

Related Experiment Video

Updated: Feb 9, 2026

Robotics in Surgery: A Modular Robotic Platform Driven Gastric Wedge Resection
07:27

Robotics in Surgery: A Modular Robotic Platform Driven Gastric Wedge Resection

Published on: February 7, 2025

1.1K

Direct target NOTES: prospective applications for next generation robotic platforms.

S Atallah1, A Hodges2, S W Larach3

  • 1Endo-Surgical Center of Florida, Department of Colorectal Surgery, Florida Hospital, Orlando, FL, USA. atallah@post.harvard.edu.

Techniques in Coloproctology
|June 2, 2018
PubMed
Summary
This summary is machine-generated.

Next-generation flexible robotic systems show promise for natural orifice transluminal endoscopic surgery (NOTES). This study demonstrated the feasibility of robotic-assisted transanal total mesorectal excision (taTME) and other NOTES procedures in a cadaveric model.

Keywords:
AppendectomyHysterectomy, VaginalMinimally Invasive Surgical ProceduresNatural Orifice Endoscopic SurgerySurgical Procedures, RoboticTaTME

More Related Videos

A Robotic Platform for High-throughput Protoplast Isolation and Transformation
10:12

A Robotic Platform for High-throughput Protoplast Isolation and Transformation

Published on: September 27, 2016

15.0K
Robotic Cochlear Implantation for Direct Cochlear Access
08:06

Robotic Cochlear Implantation for Direct Cochlear Access

Published on: June 16, 2022

4.1K

Related Experiment Videos

Last Updated: Feb 9, 2026

Robotics in Surgery: A Modular Robotic Platform Driven Gastric Wedge Resection
07:27

Robotics in Surgery: A Modular Robotic Platform Driven Gastric Wedge Resection

Published on: February 7, 2025

1.1K
A Robotic Platform for High-throughput Protoplast Isolation and Transformation
10:12

A Robotic Platform for High-throughput Protoplast Isolation and Transformation

Published on: September 27, 2016

15.0K
Robotic Cochlear Implantation for Direct Cochlear Access
08:06

Robotic Cochlear Implantation for Direct Cochlear Access

Published on: June 16, 2022

4.1K

Area of Science:

  • Minimally Invasive Surgery
  • Surgical Robotics
  • Natural Orifice Transluminal Endoscopic Surgery (NOTES)

Background:

  • Next-generation surgical robotic systems feature flexible, single-port designs for alternative anatomical access via circuitous pathways.
  • These systems offer a small footprint, suitable for specialized Natural Orifice Transluminal Endoscopic Surgery (NOTES) operations.
  • Transanal total mesorectal excision (taTME) is a key derivative procedure utilizing NOTES principles.

Purpose of the Study:

  • To demonstrate the proof-of-concept for a flexible robotic system in performing direct target NOTES operations.
  • To evaluate the feasibility of robotic-assisted taTME, transvaginal hysterectomy, transvaginal salpingo-oophorectomy, and trans-cecal appendectomy.

Main Methods:

  • Four direct target NOTES procedures were performed on a cadaveric model using a flexible robotic system (Flex® Robotic System with Colorectal Drive).
  • Procedures included robotic taTME, robotic transvaginal hysterectomy, robotic transvaginal salpingo-oophorectomy, and ex vivo robotic trans-cecal appendectomy.
  • Feasibility and operative times were recorded for each procedure.

Main Results:

  • The flexible robotic system successfully demonstrated feasibility across all four conceptual NOTES operations.
  • Robotic taTME involved a 17 cm platform excursion along a non-linear path, with the transanal dissection completed in 57 minutes.
  • Robotic transvaginal hysterectomy (78 min) and salpingo-oophorectomy (13.5 min) were completed with transvaginal extraction; the appendectomy took 24 min.

Conclusions:

  • A flexible robotic system is a viable platform for accessing anatomy via circuitous paths, suitable for direct target NOTES.
  • The demonstrated conceptual operations show potential for next-generation robotics, pending technology optimization and further preclinical validation.
  • This technology may expand the application of minimally invasive surgery through natural orifices.