Related Experiment Videos
Lnc'ed in to Cardiogenesis
Makoto Sahara1, Elif Eroglu2, Kenneth R Chien1
1Department of Cell and Molecular Biology, Karolinska Institutet, 171 77 Stockholm, Sweden; Department of Medicine-Cardiology, Karolinska Institutet, 141 86 Stockholm, Sweden.
Cell Stem Cell
|June 3, 2018
Abstract:
Despite the continuous discovery of long noncoding RNAs (lncRNAs) with critical developmental roles, our knowledge of lncRNAs that control cardiac lineage commitment is still limited. In this issue, Guo et al. (2018) report a novel lncRNA-mediated multiprotein complex assembly that directly regulates the key transcriptional programs of murine cardiogenesis.