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Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance
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Measuring and mapping the global burden of antimicrobial resistance

Simon I Hay1,2, Puja C Rao1, Christiane Dolecek3,4

  • 1Institute for Health Metrics and Evaluation, University of Washington, 2301 5th Ave, Seattle, WA, 98121, USA.

BMC Medicine
|June 5, 2018
PubMed

Insights

Antimicrobial resistance (AMR) poses a significant global health threat, causing difficult-to-treat infections with severe consequences. Better data on AMR

Area of Science:

  • Global Health
  • Infectious Diseases
  • Epidemiology

Background:

  • Antimicrobial resistance (AMR) is a growing global health crisis, leading to untreatable infections, prolonged hospital stays, increased costs, and higher mortality rates.
  • Despite widespread recognition, there is a significant lack of data on the geographical distribution, temporal trends, prevalence, and incidence of AMR.

Discussion:

  • The scarcity of comprehensive AMR data hinders accurate assessment of its health burden.
  • This data gap weakens the evidence base required for effective research and policy development to combat AMR.

Key Insights:

  • Infections resistant to antimicrobial drugs are a major threat to global health.
  • Reliable data on AMR's geographical spread and population trends are critically lacking.
  • Accurate burden assessments for AMR are difficult due to poor data availability.

Outlook:

  • Integrating mortality and morbidity data from drug-resistant infections into the Global Burden of Disease Study is proposed.
  • This integration aims to address the current policy void concerning AMR.
  • Improved data collection and reporting are crucial for future AMR mitigation strategies.
Keywords:
Anti-infective agentsAntimicrobial drugsAntimicrobial resistanceDrug-resistant infectionsGlobal burden of diseaseGlobal healthMicrobialPublic health

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