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Upconversion nanocrystal 'armoured' silica fibres with superior photoluminescence for miRNA detection
Gang Wang1, Yike Fu, Zhaohui Ren
1State Key Laboratory of Silicon Materials, School of Materials Science and Engineering, Zhejiang University, Hangzhou, Zhejiang 310027, People's Republic of China. xiang.li@zju.edu.cn.
Chemical Communications (Cambridge, England)
|June 5, 2018
Abstract:
We have fabricated a flexible membrane, consisting of SiO2 nanofibres armoured with upconversion nanoparticles, exhibiting intense photoluminescence. These assemblies were subsequently grafted with molecular beacons to produce a biosensor suitable for the detection of specific microRNA and with applications in early cancer detection and point-of-care diagnosis.