Understanding neurodegenerative disorders by MS-based lipidomics

The human body maintains a precise pH range of arterial blood between 7.35 and 7.45. Deviations result in either acidosis (pH < 7.35) or alkalosis (pH > 7.45). These conditions are further classified as respiratory or metabolic disorders based on their underlying cause.
Respiratory Acidosis and Alkalosis
Respiratory acidosis occurs due to an increase in the partial pressure of carbon dioxide PCO2 in the blood. It often arises from shallow breathing or impaired gas exchange caused by...

The self is a central aspect of human identity, encompassing an individual’s beliefs, emotions, perceptions, and experiences. It is a cognitive and psychological construct that enables individuals to interpret their traits and behaviors, influencing how they perceive themselves and interact with the world. While personality consists of stable and enduring characteristics, the self is shaped by self-perception and social experiences. This distinction highlights the dynamic nature of the...

The self-concept encompasses individuals' beliefs about themselves, structured through cognitive frameworks known as self-schemas. These schemas function as mental representations of specific traits or behaviors, influencing how self-relevant information is perceived, processed, and remembered. For example, individuals who are schematic for body weight are more likely to interpret routine experiences—such as dining out or shopping—through the lens of that trait. Conversely, those...

Deception is a pervasive aspect of human communication. Empirical studies have shown that most individuals engage in some form of deceit on a daily basis, with approximately 20% of social exchanges involving deceptive elements. Lying follows a developmental trajectory, peaking during adolescence and declining with age, possibly due to the maturation of cognitive control and social accountability.Cognitive and Social Factors in Deception DetectionDespite its prevalence, accurately detecting...

Love, as a multifaceted psychological construct, encompasses emotions, cognitive processes, and behavioral patterns that play a crucial role in human relationships. It extends beyond attraction, manifesting in deep, enduring connections that influence personal well-being and social structures.Psychological Dimensions of LoveLove differs from friendship and mere liking through its depth and intensity. While friendship is built on mutual respect, trust, and companionship, love involves emotional...

Consciousness can be defined as the state of being aware of and able to think about one's existence, sensations, and surroundings. It encompasses two major components: awareness and arousal. Awareness pertains to the recognition of environmental stimuli and internal states. At the same time, arousal refers to the physiological readiness to engage with these stimuli, which varies significantly between states like sleep and wakefulness.
Sleep, a crucial state, is characterized by reduced...