Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

9.0K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
9.0K
Distance Problem01:29

Distance Problem

75
When an object's velocity changes over time, the total distance traveled can be determined by summing small displacement intervals over short increments. This approach approximates the true distance through numerical summation and the use of integral calculus. An estimate of the total displacement can be obtained by measuring velocity at regular intervals and multiplying each value by the corresponding time step.If a runner accelerates over the first three seconds of a race, speed measurements...
75
Targets for Drug Action: Overview01:26

Targets for Drug Action: Overview

10.5K
Drugs target macromolecules to modify ongoing cellular processes. Primary drug targets include receptors, ion channels, transporters, and enzymes.
Receptors are either membrane-spanning or intracellular proteins, which upon binding a ligand, get activated and transmit the signal downstream to elicit a response. Drugs bind receptors, either mimicking the action of endogenous ligands or blocking the receptor activity to bring about a modified response. Nearly 35% of approved drugs target the G...
10.5K
Impulse01:13

Impulse

21.7K
According to Newton’s second law of motion, the rate of change of the momentum of an object is the net external force acting on it. The total change in momentum between two timepoints thus depends on both the external force acting on it and the time over which it acts. Describing this mathematically, the total change of an object’s motion is proportional to the force vector and the time over which it is applied. This product is called impulse.
Additionally, it can be shown that the...
21.7K
Target Cell Response to Hormones01:22

Target Cell Response to Hormones

5.8K
Hormones intricately bind to receptors on the surface or within target cells, initiating a cascade of cellular responses.
Notably, the cellular response can be regulated by altering the number of receptors expressed in the cell. For example, prolonged exposure to elevated hormone levels results in a gradual decline or down-regulation in the number of receptors for that specific hormone on the cell surface. Conversely, in response to low hormone levels, cells may use up-regulation, producing an...
5.8K
Impulse Response01:17

Impulse Response

768
The impulse response is the system's reaction to an input impulse. In an RC circuit, the voltage source is the input, and the capacitor's voltage is the output. The system's state and output response before and after input excitation are distinctly defined.
Kirchhoff's law forms an input signal equation, with the capacitor's current and voltage providing the output. Substituting the current and dividing by RC yields a differential equation. The output for an impulse input is the impulse...
768

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Speech Perception Development From Childhood to Adulthood Following Pediatric Cochlear Implantation: A 30-year Longitudinal Study.

Journal of pediatrics. Clinical practice·2026
Same author

The Relationship Between Vestibular, Hearing, and Balance Outcomes in Individuals With Down Syndrome.

Ear and hearing·2026
Same author

Using the gait disorientation test to measure spatial navigation in children with cochlear implants.

International journal of pediatric otorhinolaryngology·2025
Same author

Age Effects of Bone Conduction Vibration Vestibular Evoked Myogenic Potentials (VEMPs) Using B81 and Impulse Hammer Stimuli: Erratum.

Ear and hearing·2025
Same author

Effect of Age and Paradigm on Pediatric Sinusoidal Harmonic Acceleration Testing.

American journal of audiology·2025
Same author

Vestibular Evoked Myogenic Potentials and Wideband Acoustic Immittance as Screening Tools for Large Vestibular Aqueduct Syndrome.

Journal of the American Academy of Audiology·2025

Related Experiment Video

Updated: Feb 9, 2026

Testing of all Six Semicircular Canals with Video Head Impulse Test Systems
08:38

Testing of all Six Semicircular Canals with Video Head Impulse Test Systems

Published on: April 18, 2019

32.8K

Impact of Target Distance, Target Size, and Visual Acuity on the Video Head Impulse Test.

Paul D Judge1, Amanda I Rodriguez2, Kamran Barin3

  • 11 University of Nebraska Medical Center, Omaha, Nebraska, USA.

Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
|June 6, 2018
PubMed
Summary

Decreasing target distance improves video head impulse test (vHIT) gain in healthy individuals, but not those with vestibular loss (VL). Visual acuity did not significantly impact vHIT outcomes in this study.

Keywords:
distancetarget sizevHITvestibularvision

More Related Videos

The Optokinetic Response as a Quantitative Measure of Visual Acuity in Zebrafish
04:56

The Optokinetic Response as a Quantitative Measure of Visual Acuity in Zebrafish

Published on: October 9, 2013

21.1K
Author Spotlight: Assessment of Visual Acuity in Central Vision Loss Through Motion-Based Peripheral Vision Testing
06:25

Author Spotlight: Assessment of Visual Acuity in Central Vision Loss Through Motion-Based Peripheral Vision Testing

Published on: February 23, 2024

1.2K

Related Experiment Videos

Last Updated: Feb 9, 2026

Testing of all Six Semicircular Canals with Video Head Impulse Test Systems
08:38

Testing of all Six Semicircular Canals with Video Head Impulse Test Systems

Published on: April 18, 2019

32.8K
The Optokinetic Response as a Quantitative Measure of Visual Acuity in Zebrafish
04:56

The Optokinetic Response as a Quantitative Measure of Visual Acuity in Zebrafish

Published on: October 9, 2013

21.1K
Author Spotlight: Assessment of Visual Acuity in Central Vision Loss Through Motion-Based Peripheral Vision Testing
06:25

Author Spotlight: Assessment of Visual Acuity in Central Vision Loss Through Motion-Based Peripheral Vision Testing

Published on: February 23, 2024

1.2K

Area of Science:

  • Ophthalmology
  • Neurology
  • Audiology

Background:

  • The video head impulse test (vHIT) is crucial for assessing the vestibulo-ocular reflex.
  • Limited research exists on how environmental factors and visual acuity affect vHIT results.

Purpose of the Study:

  • To investigate the impact of target distance, target size, and visual acuity on vHIT outcomes.
  • To compare vHIT performance between normal controls and subjects with vestibular loss (VL).

Main Methods:

  • vHIT was performed on 38 normal controls and 8 VL subjects across three target distances and sizes.
  • Normal controls were categorized by visual acuity.
  • Key outcome measures included corrective saccade frequency, amplitude, and gain.

Main Results:

  • In normal controls, vHIT gain increased as target distance decreased, with no significant effect from target size or visual acuity.
  • VL subjects exhibited higher corrective saccade frequency and amplitude, and lower gain compared to controls.
  • The effect of decreasing target distance on gain was not observed in the VL group.

Conclusions:

  • Reduced target distance enhances vHIT gain in individuals with normal vestibular function, but not in those with vestibular loss.
  • Visual acuity appears to be a preliminary non-factor in vHIT outcomes.