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Traverse angle computations are a critical component of surveying, used to compute the internal angles within a closed traverse. A traverse consists of a series of connected lines forming a closed loop, often used for land boundary delineation or mapping. Calculating the internal angles ensures accuracy in the traverse geometry and is essential for checking survey data integrity.The process begins with known azimuths and bearings of the traverse sides. Internal angles at each vertex are...
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Novel and Innovative Hybrid Technique for Type A Aortic Dissection
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Validated Computational Model to Compute Re-apposition Pressures for Treating Type-B Aortic Dissections.

Aashish Ahuja1, Xiaomei Guo1, Jillian N Noblet2

  • 1California Medical Innovations Institute, San Diego, CA, United States.

Frontiers in Physiology
|June 6, 2018
PubMed
Summary

Endovascular repair of thoracic aortic dissection can fail due to persistent false lumen perfusion. This study determined radial pressures needed to re-appose the intimal flap, validating computational models for better stent design.

Keywords:
aortic dissectionbench testsfinite element analysisporcine aortare-apposition pressuresimulation models

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Area of Science:

  • Biomedical Engineering
  • Cardiovascular Surgery
  • Computational Mechanics

Background:

  • Endovascular repair of Stanford type B aortic dissection offers a minimally invasive option.
  • Despite initial success, over 30% of patients require re-intervention due to persistent false lumen perfusion from distal entry tears.
  • Developing stents that ensure complete false lumen closure is crucial for long-term repair durability.

Purpose of the Study:

  • To determine the radial pressures necessary to re-appose the intimal flap in a dissected porcine thoracic aorta.
  • To validate finite element analysis (FEA) models by comparing simulation results with experimental data.
  • To support the development of improved stent designs for complete false lumen sealing.

Main Methods:

  • Experimental determination of radial pressures using balloon catheter inflation on porcine aortic tissue.
  • Finite element analysis (FEA) simulations incorporating hyperelastic properties of aortic tissues.
  • Comparison of FEA predictions with bench experiment results.

Main Results:

  • FEA models accurately captured the relationship between applied pressure and radial pressure needed for intimal flap re-apposition.
  • Simulation predictions closely matched experimental findings.
  • The study quantified the radial pressures required for flap re-apposition at different aortic locations.

Conclusions:

  • Validated FEA models can accurately predict the forces required for intimal flap re-apposition.
  • Computational modeling can guide the design of next-generation endografts for thoracic aortic dissection.
  • Improved stent designs based on these models may reduce re-intervention rates by ensuring complete false lumen closure.