Study of Specific Interaction between bis(p-phenylene)-34-crown-10-based Substituted Macrocycle and Ni²

Area of Science:

• Analytical Chemistry
• Supramolecular Chemistry

Background:

• Accurate determination of Nickel (II) ions is crucial in various environmental and biological samples.
• Development of selective and sensitive probes for metal ion detection remains a significant challenge.

Purpose of the Study:

• To synthesize and characterize a novel macrocyclic host for the selective detection of Nickel (II) ions.
• To investigate the fluorescent response of the synthesized host in the presence of various metal ions.

Main Methods:

• Synthesis of a novel macrocyclic host molecule.
• Structural characterization using Nuclear Magnetic Resonance (1H-NMR, 13C NMR) and Mass Spectrometry (ESI).
• Fluorescence spectroscopy to determine selectivity and detection limits for Ni(II) ions in aqueous acetonitrile solution.

Main Results:

• The synthesized macrocyclic host demonstrated high selectivity for Ni(II) ions over other common metal ions.
• A new fluorescence band at 311 nm was observed upon complexation with Ni(II) ions.
• The probe exhibited a detection limit of 5.22 μM for Ni(II) ions in the concentration range of 10^-5–10^-4 M.

Conclusions:

• The novel bis(p-phenylene)-34-crown-10 based macrocyclic host is an effective fluorescent probe for Ni(II) ion determination.
• This represents a new class of molecules for selective recognition of Ni(II) ions.
• The developed method offers a sensitive and selective approach for quantifying Ni(II) in aqueous solutions.