Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Open and closed-loop control systems01:17

Open and closed-loop control systems

1.7K
Control systems are foundational elements in automation and engineering. They are broadly categorized into open-loop and closed-loop systems. These classifications hinge on the presence or absence of feedback mechanisms, significantly influencing the system's performance, complexity, and application.
An open-loop control system operates without feedback from the output. It consists of two primary elements: the controller and the controlled process. The controller receives an input signal...
1.7K
Morphogenesis02:19

Morphogenesis

30.5K
Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
30.5K
Feedback Loops01:01

Feedback Loops

64.6K
In most cases, excessive hormone production is prevented by negative feedback—a loop that starts with a stimulus inducing the release of a particular substance, like a hormone, to maintain a certain level before triggering a signal that results in a decrease in further release of the hormone.
64.6K
Close Relationships and Culture01:29

Close Relationships and Culture

246
Culture shapes how people approach attraction, choose partners, and build long-term relationships. While some preferences in mate selection appear consistent across cultures, such as men valuing physical attractiveness and women emphasizing financial resources, cultural contexts influence how these preferences are expressed and prioritized. Marriage extends beyond romantic ideals in many societies and is deeply embedded in social, economic, and religious frameworks.The Role of Culture in Mate...
246
Friendships and Close Friendships01:20

Friendships and Close Friendships

240
Friendship formation is a dynamic process shaped by psychological, cultural, and social factors. Friendships play a crucial role in emotional well-being, social development, and personal identity from childhood to adulthood.Childhood and Early FriendshipsFriendships in childhood often arise due to shared environments, such as school or neighborhood interactions. At this stage, proximity and common interests serve as the primary basis for connection. As children grow, their friendships evolve...
240
Whole Body Regeneration01:33

Whole Body Regeneration

4.2K
Regeneration is the process of restoring injured or lost tissues, organs, or body parts. While simpler organisms generally show greater ability to regenerate their whole body, few complex animals show similarly exceptional regeneration. For example, planarian flatworms have a unique regenerative potential making them a popular study organism among biologists to understand the mechanisms of whole body regeneration. Other organisms, such as hydra, also show extreme regeneration potential;...
4.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The dual nature of body-axis formation in Hydra regeneration: Polarity-morphology concurrency.

Biophysical journal·2026
Same author

Mechanical strain focusing at topological defect sites in regenerating Hydra.

Development (Cambridge, England)·2025
Same author

Stochastic morphological swings in <i>Hydra</i> regeneration: A manifestation of noisy canalized morphogenesis.

Proceedings of the National Academy of Sciences of the United States of America·2024
Same author

Universal calcium fluctuations in<i>Hydra</i>morphogenesis.

Physical biology·2023
Same author

Effective membrane tension: A long-range integrator of cellular dynamics.

Cell·2023
Same author

Plasticity of body axis polarity in Hydra regeneration under constraints.

Scientific reports·2022

Related Experiment Video

Updated: Feb 9, 2026

Generation and Long-term Maintenance of Nerve-free Hydra
06:33

Generation and Long-term Maintenance of Nerve-free Hydra

Published on: July 7, 2017

13.0K

Hydra Regeneration: Closing the Loop with Mechanical Processes in Morphogenesis.

Erez Braun1, Kinneret Keren1

  • 1Department of Physics & Network Biology Research Laboratories, Technion - Israel Institute of Technology, Haifa, Israel.

Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology
|June 6, 2018
PubMed
Summary

Morphogenesis relies on mechanical and bio-signaling feedback across all organism levels. Hydra regeneration demonstrates how inherited actomyosin structure guides axis formation and stabilizes via cytoskeletal reorganization.

Keywords:
Hydra regenerationclosed-loop dynamicsmechanical feedbackmorphogenesisself-organization

More Related Videos

Generation of Transgenic Hydra by Embryo Microinjection
09:10

Generation of Transgenic Hydra by Embryo Microinjection

Published on: September 11, 2014

14.8K
Measuring Glutathione-induced Feeding Response in Hydra
08:10

Measuring Glutathione-induced Feeding Response in Hydra

Published on: November 16, 2014

11.7K

Related Experiment Videos

Last Updated: Feb 9, 2026

Generation and Long-term Maintenance of Nerve-free Hydra
06:33

Generation and Long-term Maintenance of Nerve-free Hydra

Published on: July 7, 2017

13.0K
Generation of Transgenic Hydra by Embryo Microinjection
09:10

Generation of Transgenic Hydra by Embryo Microinjection

Published on: September 11, 2014

14.8K
Measuring Glutathione-induced Feeding Response in Hydra
08:10

Measuring Glutathione-induced Feeding Response in Hydra

Published on: November 16, 2014

11.7K

Area of Science:

  • Developmental biology
  • Biophysics
  • Regenerative medicine

Background:

  • Organism development (morphogenesis) requires robust coordination across multiple scales.
  • Feedback mechanisms are crucial for ensuring functional outcomes despite environmental variability.
  • Hydra are a model organism for studying regeneration due to their simplicity and regenerative capacity.

Purpose of the Study:

  • To explore the synergistic interplay between mechanical and bio-signaling processes in morphogenesis.
  • To elucidate the role of structural inheritance in guiding developmental patterns.
  • To investigate the mechanisms of pattern stabilization during regeneration.

Main Methods:

  • Investigated the role of actomyosin organization in Hydra body-axis formation.
  • Analyzed cytoskeletal reorganization dynamics during regeneration.
  • Examined the integration of mechanical feedback with biochemical processes.

Main Results:

  • Structural inheritance of actomyosin organization directs body-axis formation in Hydra regeneration.
  • Cytoskeletal reorganization, induced by inherited structure, stabilizes morphogenesis.
  • Evidence suggests mechanical feedback integrates with biochemical processes for pattern canalization.

Conclusions:

  • Morphogenesis is driven by a synergy between mechanical forces and bio-signaling pathways across all organizational levels.
  • Inherited structural information plays a key role in initiating and stabilizing developmental processes.
  • Hydra regeneration provides a model system for understanding fundamental principles of robust pattern formation.