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[Update on heart failure]

J Wintrich1, I Kindermann2, M Böhm2

  • 1Klinik für Innere Medizin III - Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Kirrbergerstraße, 66421, Homburg/Saar, Deutschland. Jan.Wintrich@uks.eu.

Herz
|June 6, 2018
PubMed

Insights

Heart failure management is crucial due to rising prevalence. Recent advances, including neprilysin inhibition, improve outcomes, but guideline-conform treatment remains vital for patients with heart failure.

Area of Science:

  • Cardiology
  • Internal Medicine
  • Pharmacology

Background:

  • Heart failure is a leading global disease, with increasing incidence due to aging populations.
  • It is the most frequent diagnosis in hospitalized patients in Germany, despite recent mortality reductions.
  • High mortality and morbidity rates necessitate guideline-conform treatment.

Purpose of the Study:

  • To review current scientific knowledge on heart failure (2017-2018) based on European Society of Cardiology guidelines.
  • To present new findings on heart failure with mid-range ejection fraction limitations.
  • To discuss innovative diagnostic and therapeutic strategies, pharmacological developments, and comorbidity management.

Main Methods:

  • Literature review of scientific knowledge from 2017-2018.
  • Focus on European Society of Cardiology guidelines for heart failure management.
  • Synthesis of information on diagnosis, therapy, and comorbidities.

Main Results:

  • Highlights recent advancements in heart failure treatment, including neprilysin inhibition.
  • Introduces new aspects of heart failure with mid-range ejection fraction.
  • Discusses innovative diagnostic tools and therapeutic approaches.

Conclusions:

  • Guideline-conform treatment is essential for managing heart failure.
  • New pharmacological options offer improved outcomes but do not eliminate risks.
  • Comprehensive management addressing comorbidities is key for heart failure patients.

Keywords:
Brain natriuretic peptideCardiac insufficiencyComorbidityDrug therapyNeprilysin

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