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[Long-Term Statin Adherence in Patients with Stable Angina after Coronary Stenting]
D I Tomilova1, Y A Karpov2, V V Lopukhova3
1National Medical Research Center for Cardiology.
Kardiologiia
|June 6, 2018
Summary
Adherence to statin therapy after percutaneous coronary intervention (PCI) decreased significantly over five years. Lower adherence was linked to increased cardiovascular complications in patients with stable angina.
Area of Science:
- Cardiology
- Pharmacology
- Public Health
Background:
- Stable angina requires long-term management.
- Percutaneous coronary intervention (PCI) is a common treatment.
- Statin therapy is crucial for managing cardiovascular risk post-PCI.
Purpose of the Study:
- To assess adherence to statin therapy in stable angina patients post-PCI.
- To investigate the relationship between statin adherence and cardiovascular complications over five years.
Main Methods:
- 574 stable angina patients undergoing elective PCI were studied.
- Statin adherence was assessed at 1 and 5 years via interviews and questionnaires.
- Cardiovascular complications (CVCs) including death, myocardial infarction, stroke, and revascularization were recorded.
Main Results:
- Statin adherence dropped from 84.5% at 1 year to 66.2% at 5 years.
- Low statin doses were common; only 8.7% achieved target low-density lipoprotein cholesterol (LDLC) levels.
- A significant association between adherence and CVCs was analyzed.
Conclusions:
- Long-term adherence to statin therapy post-PCI is suboptimal.
- Declining adherence may contribute to cardiovascular events in stable angina patients.
- Strategies to improve long-term statin adherence are needed.
Keywords:
long-term adherencelow density lipoprotein cholesterolpercutaneous coronary interventionstatinsMore Related Videos
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