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Anterior Cervical Discectomy and Fusion in the Ovine Model
Published on: October 5, 2009
The Top 50 Most-Cited Articles on Cervical Spondylotic Myelopathy
Azeem Tariq Malik1, Nikhil Jain1, Elizabeth Yu1
1Department of Orthopaedics, Ohio State University, Columbus, Ohio, USA.
Background:
Cervical spondylotic myelopathy (CSM) occurs due to chronic degenerative changes in the cervical spine causing compression of the spinal cord. CSM has been studied for decades, and numerous articles have been published on the topic. We sought to identify the top 50 most-cited articles on CSM.
Methods:
The top 50 most-cited articles were retrieved from the Scopus database using the search criteria "cervical spondylosis with myelopathy" OR "cervical spondylotic myelopathy." Levels of evidence were also calculated and descriptive and statistical analyses were carried out.
Results:
The total number of citations of the top 50 most-cited papers was 7072. The paper with the highest number of citations had 287. All articles were published between 1966 and 2010, with most published between 1990 and 1999 (n = 22). The most prolific country in terms of the total number of publications was United States, with 25 publications, followed by Japan. The majority of the articles were level IV.
Conclusions:
There is a deficiency of high-level articles in the top 50 most-cited list. This study provides an important overview of historical development of treatment methods, as well as publication trends related to this pathology. Regardless, this comprehensive list of the top 50 most-cited articles can serve as a resource for future trainees and surgeons to draw on to build their knowledge base.
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Titration Calculations: Strong Acid - Strong Base
A titration is carried out for 25.00 mL of 0.100 M HCl (strong acid) with 0.100 M of a strong base NaOH. The pH at different volumes of added base solution can be calculated as follows:
(a) Titrant volume = 0 mL. The solution pH is due to the acid ionization of HCl. Because this is a strong acid, the ionization is complete and the hydronium ion molarity is 0.100 M. The pH of the solution is then:
Punnett Squares
Reaction Yield
Bond Polarity, Dipole Moment, and Percent Ionic Character
Titration Calculations: Weak Acid - Strong Base
For the titration of 25.00 mL of 0.100 M CH3CO2H with 0.100 M NaOH, the reaction can be represented as:

