[Characterization of cortical auditory evoked potential (P1-N1-P2) in normal hearing young adults]

Objective:To explore the normal value and characteristic of cortical auditory evoked potential (P1-N1-P2) in normal hearing young adults.Method:Thirty normal hearing young people were recruited for this study. Cortical auditory evoked potential (P1-N1-P2) was performed at three different speech stimuli (/m/, /t/, /g/) and three different sound intensity (55, 65, 75 dB SPL) using the Australia HEARLab test system. Analysis of Variance (ANOVA) was used to evaluate the influence of speech stimuli and sound intensity and gender to latency and amplitude of P1-N1-P2.Result:①The normal range of latency and amplitude of P1-N1-P2 for three different speech stimuli and stimuli intensity were established. ②There were significant differences among three different speech stimuli for latency (P< 0.05) and amplitude (P< 0.05) of N1 and the latency of wave P2 (P< 0.05). ③There were no significant differences among three different stimulus intensity for the amplitude and latency of P1-N1-P2 (P> 0.05). ④There were significant differences between gender for amplitude of the wave N1 and P2 and the latency of N1 (P> 0.05).Conclusion:We initially acquired the normal range of cortical auditory evoked potential (P1-N1-P2) with different speech stimuli and different stimulus intensities in normal hearing young adults. It is also found that P1-N1-P2 values evoked by different speech stimuli showed diffrenent characteristics and stimulus frequency had a significant influence on N1 and P2 wave characteristics. This study provides reference and experience for the further application of this technology in clinical practice.