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Updated: Feb 9, 2026
10:50
Primary Culture of Human Vestibular Schwannomas
Published on: July 20, 2014
13.4K
[Tongue schwannoma：a case report].
Summary
Schwannomas, benign nerve sheath tumors, are rare in the oral cavity. This case highlights a lingual schwannoma in a teenager presenting with swallowing and speech difficulties, successfully treated with surgical excision.
Area of Science:
- Oral oncology
- Neurosurgery
- Pathology
Background:
- Schwannomas (neurilemmomas) are benign nerve sheath tumors.
- They typically present with integrated capsules and slow growth.
- While common in head and neck soft tissues (25-40%), oral cavity schwannomas are exceptionally rare (<1%).
Observation:
- A 17-year-old female presented with progressive odynophagia (painful swallowing) and dysarthria (difficulty speaking).
- Clinical examination and laryngoscopy suggested a lesion in the oral cavity.
- The patient's symptoms indicated a potential space-occupying lesion affecting critical functions.
Findings:
- A Neurilemmoma (schwannoma) of the lingual root was diagnosed.
- Preoperative laryngendoscopy and histopathological examination confirmed the diagnosis.
- Surgical excision via suspension laryngoscope was performed, with the lesion showing strong S100 protein staining.
Implications:
- This case underscores the importance of considering rare oral neoplasms in the differential diagnosis of oropharyngeal symptoms.
- Early diagnosis and surgical management are crucial for favorable outcomes in pediatric oral schwannoma cases.
- Accurate histopathological analysis, including S100 staining, is vital for confirming schwannoma diagnosis.
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