mySyntenyPortal: an application package to construct websites for synteny block analysis

Area of Science:

• Genomics
• Bioinformatics

Background:

• Comparative genomics relies on analyzing synteny blocks across species.
• Whole genome sequencing advances enable large-scale genomic studies.
• Existing tools lack customization for user-specific genome data and synteny definitions.

Purpose of the Study:

• To develop a customizable solution for creating interactive websites for synteny block analysis.
• To enable researchers to use their own genome sequences and synteny block definitions.

Main Methods:

• Developed mySyntenyPortal, a stand-alone application package.
• Provided both command-line and web-based interfaces for website construction and management.
• Demonstrated usability with a comparative genomics study of human, mouse, and cow genomes.

Main Results:

• mySyntenyPortal allows users to build and manage custom websites for comparative genomic analyses.
• Websites created with mySyntenyPortal can be easily published and accessed by others.
• The tool facilitates the identification of genes affected by genome rearrangements.

Conclusions:

• mySyntenyPortal addresses the limitations of existing web interfaces for comparative genomics.
• It empowers researchers to conduct extended comparative genomic analyses using their own data.
• The application promotes the creation of interactive websites for synteny block analysis.