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Updated: Feb 9, 2026

A Preclinical Murine Model of Hepatic Metastases
Published on: September 27, 2014
Clival chordoma with drop metastases
Faimee Erwan Muhamat Nor1, Vijayadwaja Desai2, Lee Lian Chew1
1Division of Oncologic Imaging, National Cancer Center Singapore, Singapore, Singapore.
Abstract:
Chordoma is a rare midline malignant tumor arising from embryonic remnants of the primitive notochord. The base of the skull is the second most common site of disease after the sacrococcygeal region. Intracranial chordoma constitutes about 30-35% of chordoma cases. Metastasis from chordoma is uncommon but if occurs, it tends to spread to the lungs. Cerebrospinal fluid seeding or drop metastasis is very rare. Here we describe a case of a clival chordoma with drop metastases.
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