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Fungal Phylogenomics.

Robert Riley1, Laszlo Nagy2

  • 1United States Department of Energy Joint Genome Institute, Walnut Creek, CA, USA. rwriley@lbl.gov.

Methods in Molecular Biology (Clifton, N.J.)
|June 8, 2018
PubMed
Summary
This summary is machine-generated.

Phylogenomics uses genomic data to reconstruct evolutionary histories. This study details methods for identifying gene families and analyzing them to build accurate species trees.

Keywords:
FungiGenomicsMCL clusteringOrthologsPhylogenetic treePhylogenomicsPhylogeny inferenceProtein families

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Area of Science:

  • Genomics and evolutionary biology.
  • Computational biology and bioinformatics.

Background:

  • Phylogenomics reconstructs organismal evolutionary relationships using genomic data.
  • Understanding gene and protein evolution offers insights into biological functions.

Purpose of the Study:

  • To present minimal protocols for gene family inference.
  • To utilize gene families in phylogenomic analyses for species tree reconstruction.

Main Methods:

  • Inferring gene families and encoded proteins from genomic data.
  • Applying phylogenomic analyses to these inferred families.
  • Constructing species trees based on gene family evolution.

Main Results:

  • Established protocols for gene family inference.
  • Demonstrated the utility of gene families in phylogenomic analyses.
  • Successfully inferred species trees using the described methods.

Conclusions:

  • Minimal protocols enable robust gene family inference.
  • Gene family analysis is a powerful approach for phylogenomics.
  • This work facilitates accurate reconstruction of species evolutionary histories.