Transverse venous sinus stenting for idiopathic intracranial hypertension: Safety and feasibility

Jerry Me Koovor1, Gloria V Lopez1, Kalen Riley1

  • 1Indiana University Department of Radiology and Imaging Sciences, Indianapolis, USA.

Insights

Transverse sinus stenting effectively treats idiopathic intracranial hypertension, resolving papilledema in all patients and improving headaches in most. This venous sinus stenting procedure is safe and effective for managing this condition.

Area of Science:

  • Neurology
  • Vascular Surgery
  • Interventional Radiology

Background:

  • Transverse sinus stenosis is frequently observed in idiopathic intracranial hypertension (IIH).
  • The causal relationship between transverse sinus stenosis and IIH remains unclear.
  • Previous studies have explored stenting for IIH, necessitating further evaluation.

Purpose of the Study:

  • To assess the clinical and imaging outcomes of patients with IIH who underwent transverse sinus stenting.
  • To evaluate the safety and efficacy of venous sinus stenting in this patient cohort.

Main Methods:

  • Retrospective review of clinical, venographic, and imaging data from 2011 to 2017.
  • Inclusion of 16 patients with IIH who underwent elective transverse sinus stenting.
  • Measurement of pressure gradients across stenosis before and after stenting.

Main Results:

  • Mean cerebrospinal fluid opening pressure was 408 mmH2O.
  • Mean pre-stenting pressure gradient was 21 mmHg, becoming negligible post-stenting.
  • Headaches improved in 10/16 patients; papilledema resolved in all cases.
  • Stents remained patent on follow-up imaging (CT venography).

Conclusions:

  • Venous sinus stenting is a safe and effective treatment for IIH.
  • The procedure consistently resolves papilledema.
  • Significant headache improvement is observed in a majority of patients.

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