Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ionic permeability and blood pressure.

M C Sutter

    Canadian Journal of Physiology and Pharmacology
    |April 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Investigating calcium

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Complementary medicine and the scientific method.

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·1996
    Same author

    Assigning causation in disease: beyond Koch's postulates.

    Perspectives in biology and medicine·1996
    Same author

    Lessons for atherosclerosis research from tuberculosis and peptic ulcer.

    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·1995
    Same author

    Blood cholesterol is not causally related to atherosclerosis.

    Cardiovascular research·1994
    Same author

    Effects of K+ channel openers on the vascular actions of human gamma globulin.

    European journal of pharmacology·1994
    Same author

    Wither, whether and whither pharmacology.

    Trends in pharmacological sciences·1994
    Same journal

    Next-generation therapeutics and renaissance of legacy drugs targeting the endothelin system.

    Canadian journal of physiology and pharmacology·2026
    Same journal

    Exploring the causal relationship between inflammatory cytokines and diabetic foot ulcer: A bidirectional Mendelian randomization and clinical validation study.

    Canadian journal of physiology and pharmacology·2026
    Same journal

    TRPV1, Endocannabinoid, and Opioid Systems in Analgesia: Molecular Mechanisms and Drug Development Strategies.

    Canadian journal of physiology and pharmacology·2026
    Same journal

    Association of stromal cell derived factor 1α and interferon-γ induced protein 10 with Fontan pathophysiology.

    Canadian journal of physiology and pharmacology·2026
    Same journal

    Incretins for Type 2 Diabetes.

    Canadian journal of physiology and pharmacology·2026
    Same journal

    Glucagon-like peptide 1 receptor agonists: anti-inflammatory effects in cardiovascular diseases.

    Canadian journal of physiology and pharmacology·2026
    See all related articles

    Area of Science:

    • Cardiovascular Science
    • Cell Biology
    • Hypertension Research

    Background:

    • Establishing causal links between phenomena and hypertension is challenging.
    • Ion movement studies in hypertensive tissues show conflicting results, particularly for red blood cells.
    • Evidence on ionic permeability of human blood vessels is scarce.

    Purpose of the Study:

    • To review existing literature on ion movements in hypertensive tissues.
    • To investigate altered calcium handling in blood vessels of spontaneously hypertensive rats.
    • To explore the role of calcium permeability in hypertension.

    Main Methods:

    • Literature review of ion movements in hypertensive tissues.
    • Experimental use of calcium antagonists (D-600, felodipine) on blood vessels.

    Related Experiment Videos

  • Analysis of calcium permeability in red blood cells from spontaneously hypertensive rats.

    • Main Results:

    • Conflicting evidence exists regarding red blood cell permeability changes in hypertension.
    • Leukocyte permeability data is more consistent, but human blood vessel data is lacking.
    • No significant difference was found in calcium antagonist effects on blood vessels from hypertensive rats versus controls.

    Conclusions:

    • Altered passive calcium permeability in tissues of hypertensive animals warrants further investigation.
    • The role of calcium handling in blood vessels of hypertensive rats requires more research.
    • Current findings suggest calcium permeability changes may be a promising avenue for hypertension research.