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Updated: Feb 9, 2026

Evaluation of a Reliable Biomarker in a Cecal Ligation and Puncture-Induced Mouse Model of Sepsis
Published on: December 9, 2022
[Enterobius vermicularis enteroparasite role in appendicitis cecal: Enterobiasis and appendicitis]
Luis Santos Spitale1, Rogelio Daniel Pizzi, Axel Tomas
1Cátedra de Patología FCM. UNC. luisspitale@yahoo.com.ar.
Abstract:
Sixty-five cases of enterobiasis of the cecal appendix are reported by Enterobius vermicularis or Oxiurus vermicularis. Enterobiasis is a cosmopolitan parasite5,8,13 and frequent. It is useful to establish whether it can cause appendicitis and the mechanisms involved. According to the classical literature, E. vermicularis is not a causative agent of appendicitis per se, but allows the reproduction of the germs that infiltrate the wall and produce appendicitis5,9,10. The purpose of the study is to report the prevalence of E. Vermicularis in surgical appendicitis and the anatomopathology to deduce a causal relationship. We report a sample of 2000 surgical pieces of extracted appendages (1992-2003) at the Emergency Hospital of the city of Córdoba, Argentina. On a total of 2000 pieces, we observed 65 cases of appendicular enterobiasis; in 60 cases (3.25%) there was no histopathology of acute inflammation (anodyne cecal appendix). In the remaining 5 cases (0.25%) we observed coexistence of parasites in the appendicular lumen, acute transmural inflammatory infiltrates (acute appendicitis) and fecalitos, which would support the obstructive type etiopathogenesis that leads to the surgical picture. The appendicular location of Enterobius vermicularis would favor the formation of fecalitos in light and the proliferation of germs in the wall that would lead to appendicitis. Reports indicate that the parasitic infection constitutes a percentage of the etiologies in appendicitis and fecalitos are the most common trigger, some parasites (Enterobius vermicularis) may be involved in its formation, although this percentage is minimal9,10,15,16,17 .
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