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Updated: Feb 9, 2026

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture
Published on: September 29, 2017
Chitosan-based hydrogels: From preparation to biomedical applications
Michelly C G Pellá1, Michele K Lima-Tenório2, Ernandes T Tenório-Neto2
1Department of Chemistry, State University of Maringá, Av. Colombo, 5790, CEP 87020-900, Maringá, Paraná, Brazil.
Chitosan-based hydrogels, derived from polysaccharides, show promise for biomedical applications. This review highlights recent advancements in their preparation and properties for drug delivery and tissue engineering.
Area of Science:
- Biomaterials Science
- Polymer Chemistry
- Biomedical Engineering
Background:
- Polysaccharides are increasingly utilized in biocompatible devices due to their favorable properties.
- Chitosan, a versatile polysaccharide, is extensively researched for hydrogel preparation.
- Chitosan-based hydrogels offer biocompatibility, biodegradability, and cost-effectiveness.
Purpose of the Study:
- To review recent progress in chitosan-based hydrogels.
- To focus on preparation methods, properties, and applications.
- To highlight advancements in drug delivery and tissue engineering.
Main Methods:
- Literature review of recent studies on chitosan-based hydrogels.
- Analysis of preparation techniques and material properties.
- Evaluation of applications in drug delivery and tissue engineering.
Main Results:
- Chitosan hydrogels demonstrate significant potential in biomedical fields.
- Recent research shows diverse preparation methods and tunable properties.
- Successful applications in drug delivery and tissue engineering have been documented.
Conclusions:
- Chitosan-based hydrogels are promising biomaterials for advanced biomedical applications.
- Continued research into their preparation and properties will drive innovation.
- These hydrogels offer viable solutions for drug delivery and tissue engineering challenges.
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