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Characterization data for T cell-specific Blimp-1 transgenic C57BL/6 mice

Aline Yen Ling Wang1, Charles Yuen Yung Loh2,3, Shyi-Jou Chen4,5

  • 1Center for Vascularized Composite Allotransplantation, Chang Gung Memorial Hospital, Taoyuan, Taiwan.

Data in Brief
|June 13, 2018
PubMed

This article is the first to provide characterization data regarding naive C57BL/6 transgenic mice with overexpression of B lymphocyte-induced maturation protein 1 (Blimp-1) under a T cell-specific pLCK promoter. The data presented are related to phenotype, Blimp-1 overexpression levels, T cell development and T cell proliferation for Blimp-1 transgenic mice. For further Blimp-1 overexpressed T cell findings regarding skin allotransplantation, please refer to the research article "Blimp-1 prolongs allograft survival without regimen via influencing T cell development in favor of regulatory T cells while suppressing Th1" (Wang et al., 2018) [1].

Keywords:
Blimp-1T cellTransgenic mice

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