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Updated: Feb 9, 2026

Using Near-infrared Fluorescence and High-resolution Scanning to Measure Protein Expression in the Rodent Brain
Published on: May 23, 2019
Data on specificity of [18F]GE180 uptake for TSPO expression in rodent brain and myocardium
Maximilian Deussing1, Tanja Blume1,2, Lena Vomacka1
1Dept. of Nuclear Medicine, Ludwig-Maximilians-Universität München, Munich, Germany.
Abstract:
Data in this article show radioligand uptake (to gamma counter and positron-emission-tomography) as well as polymerase chain reaction analyses of 18 kDa translocator protein (TSPO) quantification. We confirmed specificity of [18F]GE180 binding of rodent brain and myocardium by blocking experiments with prior application of non-radioactive GE180, using dynamic in vivo positron-emission-tomography and ex vivo gamma counter measurements. Expression of TSPO was compared between rodent brain and myocardium by quantitative polymerase chain reaction.
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