Related Experiment Video
Updated: Feb 9, 2026

Biofunctionalization of Magnetic Nanomaterials
Published on: July 16, 2020
Long-term clinical observations for a biofunctionalized stent: Yet to deliver their theoretical benefits
Kenta Nakamura1,2, Larry S Dean1,2
1Division of Cardiology, Regional Heart Center, University of Washington, Seattle, Washington.
Abstract:
Endothelial progenitor cells (EPCs) may allow accelerated and functional endothelialization of stents, theoretically reducing late stent complications as well reducing the duration of DAPT. In a pilot study of 193 patients at high risk of target vessel failure (TVF), the Genous EPC capturing stent (ESC) and TAXUS Liberté paclitaxel-eluting second-generation stent (PES) were similar at 5-years. Events rates appear higher for ESC within the first-year followed by higher rate of complications for PES during years 2-5. A larger randomized multi-center trials powered for non-inferiority of ECS to PES is underway.
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