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Updated: Feb 9, 2026
08:57
Simultaneous Measurement of Superoxide/Hydrogen Peroxide and NADH Production by Flavin-containing Mitochondrial Dehydrogenases
Published on: February 24, 2018
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Therapeutic potentials of superoxide dismutase
1Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
International Journal of Health Sciences
|June 14, 2018
Summary
Superoxide dismutases (SODs) are crucial antioxidants for combating oxidative stress. This review highlights SOD
Area of Science:
- Biochemistry
- Enzymology
- Antioxidant defense mechanisms
Background:
- Oxidative stress is implicated in numerous diseases.
- Superoxide dismutases (SODs) are key endogenous antioxidants.
- Reactive oxygen species (ROS) contribute to cellular damage.
Purpose of the Study:
- To review the therapeutic potential of SOD in various diseases.
- To discuss limitations of SOD in clinical applications.
- To explore advancements like SOD conjugates and mimetics.
Main Methods:
- Literature review of studies on SOD.
- Analysis of therapeutic effects in physiological and pathological conditions.
- Examination of SOD conjugates and mimetics.
Main Results:
- SOD demonstrates therapeutic effects in conditions including cancer, inflammation, and neurodegenerative diseases.
- Clinical application of SOD is limited by factors such as stability and delivery.
- SOD conjugates and mimetics show promise for enhanced efficacy.
Conclusions:
- SOD is a promising therapeutic agent for oxidative stress-related conditions.
- Overcoming SOD's limitations is crucial for its clinical translation.
- Modified SOD forms offer improved therapeutic potential.
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