Acute Myeloid Leukemia Presenting as a Central Nervous System Mass in a Child: A Case Report
Jagdish P Meena1, Menka Yadav1, Aditya K Gupta1
1Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Insights
Extramedullary leukemia, presenting as myeloid sarcoma in children with acute myeloid leukemia (AML), can cause serious symptoms. Early diagnosis and treatment of AML with myeloid sarcoma are crucial for improving patient survival rates.
Area of Science:
- Pediatric Oncology
- Hematology
- Neurology
Background:
- Extramedullary leukemia, specifically myeloid sarcoma, is a frequent manifestation in pediatric acute myeloid leukemia (AML).
- Myeloid sarcomas can present as solid tumors, often affecting the central nervous system or spine, leading to significant clinical challenges.
Abstract:
Extramedullary leukemia is common in pediatric acute myeloid leukemia (AML) and occurs as a solid tumor (myeloid sarcoma). We report a case of a child who presented with acute onset of paraparesis and found to have intracranial and paravertebral mass; subsequently, he was diagnosed as having AML on tissue biopsy. He was started on AML treatment protocol, and later he was in remission and myeloid sarcoma got cleared from intracranial and paravertebral region. Timely diagnosis and initiation of treatment are essential to improve survival in such cases.
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