Chimeric XNA: An Unconventional Design for Orthogonal Informational Systems

Tim Efthymiou1,2, Jesse Gavette1,2, Matthias Stoop1,2

  • 1Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA, 92037, USA.

Summary

Researchers created novel chimeric nucleic acids by combining compromised xeno nucleic acids (XNA) with RNA and DNA. These new molecules exhibit unique base-pairing properties, expanding the possibilities for unconventional genetic systems.

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