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Published on: September 9, 2020
Aneursymal Bone Cyst: An Uncommon Paraspinal Tumor in Children
Nilay Shah1,2, Thomas Scharschmidt3, Bonita Fung4
1Departments of Pediatrics.
Insights
Benign paraspinal tumors are rare in children without trauma. This case highlights surgical resection and USP6 gene rearrangement for diagnosing aneurysmal bone cysts in pediatric patients.
Area of Science:
- Pediatric Oncology
- Skeletal Dysplasias
- Surgical Pathology
Background:
- Paraspinal tumors in children are uncommon, particularly benign types without a history of trauma.
- Standard treatment for benign paraspinal tumors involves surgical removal and histological confirmation.
Observation:
- A pediatric patient presented with an atraumatic paraspinal mass.
- Histopathological examination revealed an aneurysmal bone cyst.
Findings:
- The aneurysmal bone cyst diagnosis was supported by the identification of a USP6 gene rearrangement.
- The patient successfully underwent gross total resection of the tumor without further treatment.
Implications:
- This case underscores the importance of considering aneurysmal bone cysts in the differential diagnosis of pediatric paraspinal masses.
- Accurate diagnosis, including genetic analysis, is crucial for appropriate management of pediatric paraspinal tumors.
Abstract:
Paraspinal tumors with benign histology in the absence of trauma rarely arise in children. Treatment of such benign tumors, in contrast to malignancies, generally consists of surgical resection of the lesion with confirmation of histology via pathologic evaluation. We present a pediatric case of an atraumatic paraspinal mass with a histologic diagnosis of aneurysmal bone cyst, and USP6 gene rearrangement supporting the histologic diagnosis. The patient underwent gross total resection of the paraspinal lesion with no additional intervention. We highlight the differential diagnosis of paraspinal tumors in children and key features that led to the diagnosis in this patient.
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